Chen Xiang (沉香) — Agarwood | TCM Herb Guide

Key Takeaways

  • Nature: Warm | Taste: Acrid, Bitter
  • Category: Herbs that Regulate Qi
  • Latin: Aquilariae Lignum Resinatum

At a Glance

  • Herb: Chen Xiang
  • Chinese name: 沉香 (Chén Xiāng)
  • Latin name: Aquilaria sinensis / agallocha resinous heartwood
  • Nature: Warm
  • Taste: Acrid / Bitter
  • Meridian: Spleen / Stomach / Kidney
  • Category: Herbs that Regulate Qi
  • Introduction: Chen Xiang (沉香), Lignum Aquilariae Resinatum, is the resin-impregnated heartwood of Aquilaria sinensis or A. agallocha, formed when the tree responds to injury or fungal infection by producing a dense aromatic resin. One of the most valued aromatic herbs and incense materials, it moves qi downward, warms the middle, and assists the kidney in grasping qi. Modern research identifies sesquiterpenes responsible for its analgesic, antispasmodic, and central nervous system-sedating properties.

Action

  • Moves qi downward and relieves pain
  • Warms the middle and stops vomiting
  • Assists the kidney to grasp qi (treats deficiency asthma)
  • Warms the kidney and relieves cold abdominal pain

Clinical Application

  • Qi stagnation with cold: chest and abdominal pain, distension — combines with Wu Yao, Mu Xiang, Yan Hu Suo
  • Stomach cold with vomiting, hiccup, belching — combines with Ding Xiang, Rou Gui, Ban Xia
  • Kidney deficiency failing to grasp qi: chronic asthma, dyspnea on exertion — combines with Fu Zi, Bu Gu Zhi, Rou Gui
  • Cold hernia pain (lower abdominal cold pain radiating to genitals) — combines with Wu Yao, Xiao Hui Xiang
  • Constipation from cold accumulation and qi stagnation — combines with Wu Yao, Da Huang

Precautions

  • Dosage: 1–5 g in decoction (add near end of cooking — volatile); 0.5–1 g as powder
  • Do not decoct for a long time — volatile aromatics dissipate quickly
  • Contraindicated in yin deficiency with empty heat or excess fire patterns
  • Contraindicated in qi deficiency without stagnation
  • Very expensive — often substituted with Chen Xiang powder or oil; verify authenticity
  • Avoid in pregnancy

Formula

  • Chen Xiang Jiang Qi Tang (沉香降气汤): Chen Xiang, Sha Ren, Zhi Gan Cao, Yan Hu Suo — moves qi downward, relieves cold pain
  • Si Mo Tang (四磨汤): Chen Xiang, Wu Yao, Bing Lang, Ren Shen — moves qi, relieves constraint, descends rebellious qi
  • Chen Xiang San (沉香散): Chen Xiang, Rou Gui, Fu Zi, Bu Gu Zhi — warms kidney, assists grasping qi for deficiency asthma
  • Su He Xiang Wan (苏合香丸): includes Chen Xiang to open orifices and move qi in acute obstruction patterns

Combinations

  • 乌药 (Wū Yào) + 人参 (Rén Shēn) — kidney yang deficiency with cold qi rising causing chest and abdominal pain, wheezing (四磨汤). 2. 附子 (Fù Zǐ) + 肉桂 (Ròu Guì) — kidney yang deficiency with cold feet, frequent urination, and difficulty breathing on exertion. 3. 木香 (Mù Xiāng) + 槟榔 (Bīng Láng) — qi stagnation with abdominal distension and pain. 4. 半夏 (Bàn Xià) + 生姜 (Shēng Jiāng) — stomach cold with nausea and hiccup. 5. 肉苁蓉 (Ròu Cōng Róng) + 巴戟天 (Bā Jǐ Tiān) — kidney yang deficiency with constipation. Source: 济生方 (四磨汤), 本草纲目.

Pharmacological Effects

  • chromones
    • Bronchodilatory: relax airway smooth muscle via β₂ receptor activation
    • Bronchodilatory: reduce histamine-induced bronchoconstriction
    • Antidiabetic: improve insulin sensitivity and reduce postprandial glucose
  • sesquiterpenes
    • Analgesic: modulate opioid receptors
    • Analgesic: reduce acetic acid-induced writhing
  • Antinausea/antiemetic
    • reduces cisplatin-induced emesis
    • inhibits 5-HT₃ receptors
  • agarospirol
    • Sedative: modulates GABA-A
    • Sedative: reduces spontaneous locomotion and anxiety
  • 2-(2-phenylethyl)chromones
    • Antitumor: inhibit NF-κB and induce apoptosis in lung and colon cancer lines

Classic Description

  • Ming Yi Bie Lu (《名医别录》): ‘Treats wind-water toxin swelling, eliminates foul qi, governs Heart and abdominal pain, sudden turmoil and malevolence, pathogenic ghost-entry qi; clears the human spirit; decocted in wine and taken is appropriate for all.’
  • Ben Cao Gang Mu (《本草纲目》): ‘Treats upper heat with lower cold, qi counterflow and rapid breathing, Large Intestine deficiency obstruction, urinary qi strangury, and male seminal cold.’
  • Ben Cao Bei Yao (《本草备要》): ‘Acrid and bitter, warm in nature; among all woods this one alone sinks in water; hence it can descend qi, precipitate phlegm and drool, warm essence and strengthen yang, move qi and stop pain.’

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