Shan Ci Gu (山慈菇) — Pleione Bulb | TCM Herb Guide

Key Takeaways

  • Nature: Cool | Taste: Slightly Acrid, Sweet
  • Category: Herbs that Clear Heat and Resolve Toxicity
  • Latin: Cremastrae seu Pleiones Pseudobulbus

At a Glance

  • Herb: Shan Ci Gu
  • Chinese name: 山慈菇 (Shān Cí Gū)
  • Latin name: Cremastrae seu Pleiones Pseudobulbus
  • Nature: Cool
  • Taste: Sweet / Slightly Acrid
  • Meridian: Liver / Spleen
  • Category: Herbs that Clear Heat and Resolve Toxicity
  • Introduction: Shan Ci Gu (山慈菇), Pseudobulbus Cremastrae seu Pleiones, is the dried pseudobulb of Cremastra appendiculata or Pleione bulbocodioides, terrestrial orchids native to mountain forests. A potent heat-clearing, toxin-resolving herb, it specializes in dissipating masses, reducing nodules, and treating tumors — making it one of the most important anti-cancer herbs in TCM. Its colchicine content accounts for anti-mitotic, antitumor, and anti-gout properties documented in modern research.

Action

  • Clears heat and resolves toxicity
  • Dissipates masses and reduces nodules
  • Reduces swelling and relieves pain
  • Anti-tumor (modern clinical use)

Clinical Application

  • Scrofula, thyroid nodules, lymphoma — combines with Xuan Shen, Mu Li, Zhe Bei Mu
  • Tumors: breast cancer, gastric cancer, liver cancer (adjunctive) — combines with Ban Zhi Lian, Bai Hua She She Cao
  • Carbuncles, toxic sores, snake bites — topical and internal
  • Gout flare (acute) from damp-heat — combines with Huang Bai, Cang Zhu, Yi Yi Ren
  • Breast lumps and thyroid nodules from phlegm-fire stagnation

Precautions

  • Dosage: 3–9 g in decoction; 1.5–3 g as powder
  • Contains colchicine — toxic in large doses; do not exceed recommended dose
  • Contraindicated in pregnancy
  • Contraindicated in deficiency cold patterns without toxic heat accumulation
  • Long-term use requires liver function monitoring due to colchicine content
  • Topical use: grind to paste for external sores

Formula

  • Zi Jin Ding (紫金锭 / Yu Shu Dan): Shan Ci Gu, Wen Mao, Zhu Sha, Da Ji, Wu Bei Zi, Qian Jin Zi — resolves toxicity, disperses masses; classical antidote pill
  • Shan Ci Gu + Xuan Shen + Mu Li + Zhe Bei Mu: standard combination for scrofula and thyroid nodules
  • Modern anti-cancer formula: Shan Ci Gu, Ban Zhi Lian, Bai Hua She She Cao, Ban Xia — phlegm-toxin tumor formula

Combinations

  • Cremastra Pseudobulb (山慈菇) + Musk (麝香) + Realgar (雄黄) → Zi Jin Ding (紫金锭): clear heat toxin, resolve phlegm; emergency toxic conditions
  • Cremastra Pseudobulb (山慈菇) + Zhejiang Fritillary Bulb (浙贝母) + Oyster Shell (牡蛎) → resolve phlegm, soften hardness, disperse nodules; scrofula, thyroid nodules, and subcutaneous masses

Pharmacological Effects

  • Antitumor
    • alkaloids inhibit cell division — colchicine-like effects in related species
  • antibacterial; anti-inflammatory; antiviral; resolves phlegm masses and nodules; immunomodulatory; NOTE: toxic in large doses — use within therapeutic range

Classic Description

  • Ben Cao Shi Yi (《本草拾遗》): ‘Governs carbuncle swelling, sore fistula, scrofula nodules, etc.; grind with vinegar and apply topically.’
  • Ben Cao Gang Mu (《本草纲目》): ‘Cremastra Pseudobulb governs boil swelling; attacks toxin and breaks the skin; resolves all toxins, parasite toxin, and wounds from snake, insect, and rabid dog bites.’
  • Ben Cao Bei Yao (《本草备要》): ‘Disperses carbuncle swelling; resolves all toxins; treats carbuncles and abscesses, malignant sores, scrofula nodules, and snake and insect bites.’
  • Wai Ke Zheng Zong (《外科正宗》): ‘Treats carbuncles, upper back abscesses, boil toxin, and scrofula — using Zi Jin Ding ground with vinegar for external application.’

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